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Sepsis: A quiet assassin. 

  • Writer: Rtr. Zeeniya Hassan
    Rtr. Zeeniya Hassan
  • Jan 7
  • 3 min read

Did you know that nearly 48.9 million cases of sepsis occur globally each year, resulting in about 11 million deaths, which is roughly 20% of all deaths worldwide?  Sepsis is a life-threatening condition caused by the body's aggressive immune response to an infection spiraling out of control, leading to widespread inflammation, tissue damage, organ failure, and, if untreated, death within mere hours or days. This blog will explain why sepsis is often called a ‘quiet assassin,’ a condition with a massive impact but low public awareness, making it difficult to prevent or treat effectively.


The body's immune system fights off infections such as bacterial, fungal, parasitic, and viral in the blood every single day. In an aggressive and erratic attempt to stop the infection from spreading, the immune system causes widespread inflammation, tissue damage, organ failure, and if untreated death. Despite being a leading cause of mortality, sepsis remains under-recognized by the general public and even healthcare professionals.


Symptoms vary depending on the origin of infection, the damage caused and how far inflammation has spread. Sepsis can affect anyone, but certain groups are higher at risk: 

  • People with weakened immune systems that have infections often

  • Infants and young children

  • Adults aged 65 and older

  • Individuals with chronic illnesses such as diabetes or liver disease


It’s very important for quick diagnosis and prompt treatment for people with infections that may go on to develop sepsis. There are no strict criteria to diagnose sepsis, but must be done with intensive care. The CDC and other health organizations use the acronym IT’S ABOUT TIME to help people remember the warning signs : 


  • Temperature

  • Infection

  • Mental decline

  • Extremely ill


Sepsis is a medical emergency. Rapid diagnosis and treatment, ideally within the first hour, are essential to improve outcomes and save lives. Treatment typically involves, administraton of antibiotics, IV fluids,vasopressor medications, fluid resuscitation, and in some cases, surgeries to remove the damaged tissues, which are crucial for improving patient outcomes. 


With quick diagnosis and treatment, many people with mild sepsis survive. With prompt treatment, many people with sepsis recover completely and return to leading normal lives. But others may experience long-term effects.the risk can be reduced by:

  • Practicing good hygiene (frequent handwashing, covering wounds)

  • Staying up-to-date with vaccinations

  • Managing chronic health conditions

  • Using antibiotics appropriately

  • Seeking medical attention promptly for suspected infections


Why it matters:

  • September is Sepsis Awareness Month, a time when health organizations worldwide emphasize the importance of understanding sepsis, recognizing its signs, and acting quickly.Even If you survive sepsis, you’ll more than likely need rehabilitation before returning home. Your body has been through a lot. Healthcare providers will help you restore your health, and you’ll slowly learn how to take care of yourself again.


  • Research is ongoing to identify better biomarkers for early sepsis detection and to understand the complex pathophysiology of the disease. Sepsis is a serious and often misunderstood medical emergency, but knowledge is our most powerful tool in fighting it. By recognizing the warning signs, acting quickly, and spreading awareness, we can help save lives, maybe even our own or those of our loved ones. Remember, when it comes to sepsis, every second counts. Stay informed, stay vigilant, and never hesitate to seek medical help if you suspect something is wrong. Together, we can turn the tide against this silent threat.



 
 
 

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The Rotaract Club of Royal Institute of Colombo.

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